THE 5-SECOND TRICK FOR PKRRATING

The activated enzyme then phosphorylates its major substrate, the translational initiation element eIF2α. The resulting translational arrest blocks viral replication. PKR belongs to your conserved family of 4 protein kinases (PKR, PERK, GCN2, HRI) that every one phosphorylate eIF2α in reaction to various stimuli12, triggering the integrated tensi